Blar i forfatter "Pasing, Yvonne"

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    • Changes in the human transcriptome upon vitamin D supplementation 

      Pasing, Yvonne; Fenton, Christopher Graham; Jorde, Rolf; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-19)
      Vitamin D is hydroxylated in the liver and kidneys to its active form, which can bind to the vitamin D receptor (VDR). The VDR is present in a wide variety of different cells types and tissues and acts as a transcription factor. Although activation of the VDR is estimated to regulate expression of up to 5% of the human genome, our study is the first analysing gene expression after supplementation ...

    • Ulcerative colitis: Functional analysis of the in-depth proteome 

      Schniers, Armin; Goll, Rasmus; Pasing, Yvonne; Sørbye, Sveinung; Florholmen, Jon; Hansen, Terkel (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-29)
      <p><i>Background - </i>Ulcerative colitis (UC) is one major form of inflammatory bowel disease. The cause and the pathophysiology of the disease are not fully understood and we therefor aim in this study to identify important pathophysiological features in UC from proteomics data. <p><i>Methods - </i>Colon mucosa biopsies from inflamed tissue of untreated UC patients at diagnosis and from healthy ...